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Radionuclide ventricular function studies can be broadly divided into two types: is a physiologic, safe, noninvasive procedure that is easy to perform and to repeat without undesirable side effects or discomfort to the patient.

It is much less expensive than either cardiac catheterization or conventional x-ray contrast angiography.

Quantitative indicators of cardiac function include heart rate, cardiac output, arterial pressure, left ventricular end-diastolic pressure, stroke volume and ejection fraction.

Ventricular volumes, ejection fraction and exercise hemodynamics are the most important measures of cardiac performance, providing global and regional information about cardiac pump function.

The first attempt to assess cardiac function using radiotracers was made in 1948 by the renowned American Cardiologist Dr. With an IV bolus of sodium-24, and with an ink-writing GM tube placed over a patient’s pericardium, Dr.

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The MUGA scan has been used for decades to evaluate global and regional wall motion, to calculate the excursion of blood from the left or right ventricles, determine ventricular volumes and to obtain a stroke volume ratio.

With the first pass technique we may quickly assess wall motion abnormalities, left and right ejection fractions and ventricular volumes, calculate transit times and cardiac output and evaluate intracardiac shunts.